Menocalm is a hop-based dietary supplement that helps reduce symptoms associated with menopause, such as hot flashes, sweating, restlessness, and irritability. It contains a variety of hops rich in 8-prenylnaringenin (isoflavonoid), which acts on estrogen receptors (β) and (β), especially in the hypothalamus, directly targeting hot flashes. It also contains bitter acids with hypnotic and sedative properties, improving some of the symptoms associated with hot flashes, such as insomnia and irritability.